Preparation of compounds similar to 4- (4’- methoxyphenyl)- 3- buten- 2- one (Product A) and 1, 5- bis (4’- methoxyphenyl)- 1, 4- pentadien- 3- one (Product B)

Abstract

4-(4-methoxyphenyl)-3-buten-2-one (Product A) has been synthesized from p-anisaldehyde and acetone via aldol condensation. The reaction was performed at room temperature under basic condition to give yellow solid of product. This one-pot synthesis involves dehydrogenation, aldol condensation and hydrogenation of C=C. the base catalyzes the dehydrogenation, hydrogenation steps and catalyzes the C–C coupling (aldol) process. Than we repeat the reaction, this time using (Product A) as the source ketone to form the bis-addition 1,5-bis(4'-methoxyphenyl)-1,4-pentadien-3-one (Product B).We tried to re-apply the same steps to benzaldehyde with acetone and vanillin with acetone under basic condition to produce compounds of 4- phenylbut- 3- en- 2- one (product C),1, 5- diphenylpenta- 1, 4- dien- 3- one (product D), (E)- 4- (4- hydroxy- 3- methoxyphenyl) but- 3- en-2- one (product E) and (1E, 4E)- 1, 5- bis (4- hydroxy- 3- methoxyphenyl)penta- 1, 4- dien- 3- one (product F).These products were characterized using IR spectroscopy and the UV spectrometer.