CONTENU PHENOLIQUE ET ACTIVITÉS BIOLOGIQUES DES FEUILLES DE L’ÉSPÈCE Bunium mauritanicum

Abstract

Modern medicine uses many compounds derived from plants as an essential raw material in the pharmaceutical industry. Bunium mauritancum is one of the many plants which, throughout history, have had a reputation in the medical field. The main objective of this study was to evaluate bioactive substances, particularly polyphenols and flavonoids, as well as an evaluation of the antioxidant and anti-inflammatory activity of extracts from the leaves of this species. The sample was subjected to maceration in methanol, and the yield obtained from the aerial part is of the order of 3.1%. The quantitative analysis of total phenols and flavonoids revealed the presence of significant amounts respectively 123.80 ± 1.99 μg EAG / mg and 76.79 ± 9.039 μg EQ / mg of extract. Moreover, the methanoic extract of the leaves contains a strong reducing power and antioxidant capacities with respect to the DPPH radical with an IC50 of 19.36 mg / ml. The in vitro evaluation of the anti-inflammatory activity of extracts from the leaves showed a percentage inhibition of 40.11%. Our results demonstrate the remarkable potential of this plant as a valuable source of antioxidants exhibiting remarkable effects biologically