EFFET PROTECTEUR DES GRAINS DE POLLEN DE PALMIER (Phœnix dactyliferaL.) SUR LA FONCTION IMMUNITAIRE DES LAPINS MALES APRES L’EXPOSITION AU DIETHYLE PHTALATE

Abstract

The aim of this work is to evaluate the protective effect of palm pollen grains (phoenix dactylifera L (DPP)) against the toxicity of, (DEP) which is one of the elements having a toxic effect on organisms living.

The study was conducted on New Zealand adult male rabbits for 30 days. The animals were divided into four groups. Group I received distilled water and was taken as a control, while Groups II, III and IV received daily 240 mg / kg / day of (DPP), 330 ml / kg / day of (DEP) and an association of 330ml / kg / day of (DEP) with 240 mg / kg / day of (DPP), respectively. After treatment, the rabbits were sacrificed and the organs were removed, fixed in 10% formalin and stained with hematoxylin and eosin. The blood was collected in tubes to evaluate different biochemical and hematological parameters. The results indicate that treatment with (DEP) caused a decrease in body weight and thymus weight, as well as a drop in white blood cell count and percentage of granulocytes and an increase in lymphocytes compared to the control group.

The administration of palm pollen seeds (DPP) showed a positive improvement in all parameters studied. Our results confirm that DEP can effect changes in immune function and, therefore, show that DPP treatment can mitigate the deleterious effects of DEP.